Expand this page

Publications - Craig T. Martin

   see also recent seminars

Quick click on the following to go to:


"Insights into the Mechanism of Initial Transcription in E coli RNA Polymerase. Energetic Mechanisms Leading to Initial Complex Instability and Abortive Cycling," Satamita Samanta & Craig T. Martin, J. Biol. Chem. 288, 31993-32003, 2013..

"New Insights into the Mechanism of Initial Transcription: the T7 RNA Polymerase Mutant P266L Transitions to Elongation at Longer RNA Lengths than Wild Type," Luis Ramírez-Tapia & Craig T. Martin, J. Biol. Chem. 287, 37352-37361, 2012.

"Direct Tests of the Energetic Basis of Abortive Cycling in Transcription," Ankit V. Vahia & Craig T. Martin, Biochemistry 50, 7015-7022, 2011.

"Transcription Elongation Complex Stability: The Topological Lock," Xiaoqing Liu & Craig T. Martin, J. Biol. Chem. 284, 36262-36270, 2009.

"Transcription: Initiation," Craig T. Martin & Olga S. Mironova, Wiley Encyclopedia of Chemical Biology, Vol 4 (Editor: Tadhg P. Begley), 584-595, 2009.

"Dissociation of halted T7 RNA polymerase elongation complexes proceeds via a forward translocation mechanism," Yi Zhou, Deanna M. Navaroli, Metewo Selase Enuameh, & Craig T. Martin, Proc. Natl. Acad.Sci., U.S.A. 104, 10352-10357, 2007.

"Twisted or shifted? Fluorescence measurements of late intermediates in transcription initiation by T7 RNA polymerase"," Rosemary S. Turingan, Karsten Theis, & Craig T. Martin, Biochemistry 46, 6165-6168, 2007.

"Structural Confirmation of a Bent and Open Model for the Initiation Complex of T7 RNA Polymerase"," Rosemary S. Turingan, Cuihua Liu, Mary E. Hawkins, & Craig T. Martin, Biochemistry 46, 1714-1723, 2007.

"Observed instability of T7 RNA polymerase elongation complexes can be dominated by collision-induced "bumping"," Yi Zhou and Craig T. Martin, J. Biol. Chem. 281, 24441-24448, 2006.

"Mechanism of instability in abortive cycling by T7 RNA polymerase," Peng Gong and Craig T. Martin, J. Biol. Chem. 281, 23533-23544, 2006.

"Light-Regulated Release of DNAand Its Delivery to Nuclei by Means of Photolabile Gold Nanoparticles," Gang Han, Chang-Cheng You, Byoung-jin Kim, Rosemary S. Turingan, Neil S. Forbes, Craig T. Martin, & Vincent M. Rotello, Angew. Chem. Int. Ed. 45, 3165-3169, 2006    (supplementary info available).
  See reports in NCI Nanotech News and Nature Materials

"Stability of Gold Nanoparticle-Bound DNA toward Biological, Physical, and Chemical Agents," Gang Han, Craig T. Martin, and Vincent M. Rotello, Chem Biol Drug Des. 67 78-82, 2005

"Controlled Recovery of the Transcription of Nanoparticle-Bound DNA by Intracellular Concentrations of Glutathione," Gang Han, Nandini S. Chari, Ayush Verma, Rui Hong, Craig T. Martin, and Vincent M. Rotello, Bioconjugate Chem. 16 1356-1359, 2005

"Structure and Function in Promoter Escape by T7 RNA Polymerase," Craig T. Martin, Edward A. Esposito, Karsten Theis, & Peng Gong, Prog Nucl Acids Res & Mol Biol, Kivie Moldave, Ed., 80 323-347, 2005

"Topological and conformational analysis of the initiation and elongation complex of T7 RNA polymerase suggests a new twist," Karsten Theis, Peng Gong and Craig T. Martin, Biochemistry, 43, 12709-12715, 2004

"Initial bubble collapse plays a key role in the transition to elongation in T7 RNA polymerase," Peng Gong, Edward A. Esposito and Craig T. Martin, J. Biol. Chem. 279, 44277-44285, 2004.

"Crosslinking of Promoter DNA to T7 RNA Polymerase Does Not Prevent Formation of a Stable Elongation Complex," Edward A. Esposito and Craig T. Martin, J. Biol. Chem. 279, 44270-44276, 2004.

"Evaluation of fluorescence spectroscopy methods for mapping melted regions of DNA along the transcription pathway," Craig T. Martin, Andrea Újvári, & Cuihua Liu, Methods Enzymol. 371, 13-33, 2003.

"Binding of the Priming Nucleotide in the Initiation of Transcription by T7 RNA Polymerase," Iaroslav Kuzmine, Philip A. Gottlieb, & Craig T. Martin, J. Biol. Chem. 278, 2819-2823, 2003.

"Promoter Clearance by T7 RNA Polymerase: Initial Bubble Collapse and Transcript Dissociation Monitored by Base Analog Fluorescence," Cuihua Liu & Craig T. Martin, J. Biol. Chem. 277, 2725-2731, 2002.
  Selected as a "Must Read" by Faculty of 1000!

"Interrupting the Template Strand of the T7 Promoter Facilitates Translocation of the DNA During Initiation, Reducing Transcript Slippage and the Release of Abortive Products," Manli Jiang, Minqing Rong, Craig Martin, and William T. McAllister, J. Mol. Biol. 310, 509-522, 2001.

"Inhibition of DNA transcription using cationic mixed monolayer protected gold clusters," Catherine M. McIntosh, Edward A. Esposito, III, Andrew K. Boal, Joseph M. Simard, Craig T. Martin, & Vincent M. Rotello, J. Am. Chem. Soc. 123, 7626-7629, 2001.

"Structure in Nascent RNA Leads to Termination of Slippage Transcription by T7 RNA Polymerase," Iaroslav Kuzmine, Philip A. Gottlieb, & Craig T. Martin, Nucl. Acids Res. 29, 2601-2606, 2001.

"Fluorescence Characterization of the Transcription Bubble in Elongation Complexes of T7 RNA Polymerase ," Cuihua Liu & Craig T. Martin, J. Mol. Biol. 308, 465-475, 2001.
  Reviewed in Current Opinions in Structural Biology

& "Pre-steady State Kinetics of Initiation of Transcription by T7 RNA Polymerase - A New Kinetic Model ," Iaroslav Kuzmine & Craig T. Martin, J. Mol. Biol. 305, 559-566, 2001.

"Evidence for DNA bending at the T7 RNA polymerase promoter," Andrea Újvári & Craig T. Martin, J. Mol. Biol. 295, 1173-84, 2000.

"Identification of a Minimal Binding Element within the T7 RNA Polymerase Promoter," Andrea Újvári & Craig T. Martin, J. Mol. Biol. 273, 775-781, 1997.

"Positioning of the Start Site in the Initiation of Transcription by T7 RNA Polymerase," Benjamin F. Weston, Iaroslav Kuzmine, & Craig T. Martin, J. Mol. Biol 272, 21-30, 1997.

"Thermodynamic and Kinetic Measurements of Promoter Binding by T7 RNA Polymerase," Andrea Újvári & Craig T. Martin, Biochemistry 35, 14574-14582, 1996.

"Major Groove Recognition Elements in the Middle of the T7 RNA Polymerase Promoter," Tong Li, Hoi Hung Ho, Maribeth Maslak, Charlie Schick & Craig T. Martin, Biochemistry 35, 3722-3727, 1996.

"Identification of Essential Amino Acids Within the Proposed CuA Binding Site in Subunit II of Cytochrome c Oxidase," Henry Speno, M. Reza Taheri, Derek Sieburth, and Craig T. Martin, J. Biol. Chem. 270, 25363-25369, 1995.

"Tests of a Model of Specific Contacts in T7 RNA Polymerase-Promoter Interactions," Charlie Schick and Craig T. Martin, Biochemistry 34, 666-672, 1995.

"Effects of Solution Conditions on the Steady State Kinetics of Initiation of Transcription by T7 RNA Polymerase," Maribeth Maslak and Craig T. Martin, Biochemistry, 33, 6918-6924, 1994.

"Kinetic Analysis of T7 RNA Polymerase Transcription Initiation From Promoters Containing Single Stranded Regions," Maribeth Maslak and Craig T. Martin, Biochemistry 32, 4281-4285, 1993.

"Identification of Specific Contacts in T3 RNA Polymerase-Promoter Interactions: Kinetic Analysis using Small Synthetic Promoters," Charlie Schick and Craig T. Martin, Biochemistry 32, 4275-4280, 1993.

"Tests of a Model for Promoter Recognition by T7 RNA Polymerase: Thymine Methyl Group Contacts," Maribeth Maslak, Martha D. Jaworski, and Craig T. Martin, Biochemistry 32, 4270-4274, 1993.

"Reaction of Single-Stranded DNA with Hydroxyl Radical Generated by Iron(II)-Ethylenediaminetetraacetic Acid," Richard V. Prigodich & Craig T. Martin, Biochemistry 29, 8017-8019, 1990.

"T7 RNA Polymerase Interacts with Its Promoter from One Side of the DNA Helix," Daniel K. Muller, Craig T. Martin, and Joseph E. Coleman, Biochemistry 28, 3306-3313, 1989.

"T7 RNA Polymerase Does Not Interact with the 5'-Phosphate of the Initiating Nucleotide," Craig T. Martin and Joseph E. Coleman, Biochemistry 28, 2760-2762, 1989.

"Processivity of Proteolytically Modified Forms of T7 RNA Polymerase," Daniel K. Muller, Craig T. Martin, and Joseph E. Coleman, Biochemistry 27, 5763-5771, 1988.

"Processivity in Early Stages of Transcription by T7 RNA Polymerase," Craig T. Martin, Daniel K. Muller, and Joseph E. Coleman, Biochemistry 27, 3966-3974, 1988.

"On the Nature of Cysteine Coordination to CuA in Cytochrome c Oxidase," Craig T. Martin, Charles P. Scholes, and Sunney I. Chan, J. Biol. Chem. 263, 8420-8429, 1988.

"A Proposal for the Site and Mechanism of Redox-Linked Proton Translocation in Cytochrome c Oxidase," Sunney I. Chan, Peter Mark Li, Thomas Nilsson, Jeff Gelles, David F. Blair, and Craig T. Martin, Prog. Clin. Biol. Res. 274, 731-747, 1988.

"Kinetic Analysis of T7 RNA Polymerase-Promoter Interactions with Small Synthetic Promoters," Craig T. Martin and Joseph E. Coleman, Biochemistry 26, 2690-2696, 1987.

"Zinc Metalloproteins Involved in Replication and Transcription," David P. Giedroc, Kathleen M. Keating, Craig T. Martin, Kenneth R. Williams, and Joseph E. Coleman, J. Inorg. Biochem. 28, 155-169, 1986.

"Transcription by T7 RNA Polymerase Is Not Zinc-Dependent and Is Abolished on Amidomethylation of Cysteine-347", Garry C. King, Craig T. Martin, Thang T. Pham, and Joseph E. Coleman, Biochemistry 25, 36-40, 1986.

"The Identification of Histidine Ligand(s) to Cytochrome a in Cytochrome c Oxidase," Craig T. Martin, Charles P. Scholes, and Sunney I. Chan, J. Biol. Chem. 260, 2857-2861, 1985.

"The Metal Centers of Cytochrome c Oxidase: Structure and Function," Sunney I. Chan, Craig T. Martin, Hsin Wang, David F. Blair, Jeff Gelles, Gary W. Brudvig, and Tom H. Stevens, in Biochemical and Biophysical Studies of Proteins and Nucleic Acids, Tung-Bin Lo, Teh-Yung Liu, and Choh-Hao Li, eds., Elsevier, New York, 219-239, 1984.

"Energetics and Molecular Dynamics of the Proton Pumping Photocycle in Bacteriorhodopsin," Robert R. Birge, Albert F. Lawrence, Thomas M. Cooper, Craig T. Martin, David F. Blair, and Sunney I. Chan, in Nonlinear Electrodynamics in Biological Systems, W. Ross Adey and Albert F. Lawrence, eds., Plenum, New York, 107-120, 1984.

"Structural Studies on the Metal Centers of Cytochrome c Oxidase," Jeff Gelles, David F. Blair, Craig T. Martin, Hsin Wang, and Sunney I. Chan, in Frontiers in Biochemical and Biophysical Studies of Proteins and Membranes, Teh-Yung Liu, Shunpei Sakakibara, Alan N. Schechter, Kunio Yagi, Haruaki Yajima, and Kerry T. Yasunobu, eds., Elsevier, New York, 259-277, 1983.

"The Structure of the Metal Centers in Cytochrome c Oxidase," Sunney I. Chan, Craig T. Martin, Hsin Wang, Gary W. Brudvig, and Tom H. Stevens, in The Coordination Chemistry of Metalloenzymes, I. Bertini, R. S. Drago, and C. Luchinat, eds., D. Reidel Pub. Co., Boston, 313-328, 1983.

"A Resonance Raman Investigation of Perturbed States of Tree and Fungal Laccase," D. F. Blair, G. W. Campbell, V. Lum, C. T. Martin, H. B. Gray, B. G. Malmström, and Sunney I. Chan, J. Inorg. Biochem. 19, 65-73, 1983.

"The Metal Centers of Cytochrome c Oxidase: Structures and Interactions," David F. Blair, Craig T. Martin, Jeff Gelles, Hsin Wang, Gary W. Brudvig, Tom H. Stevens, and Sunney I. Chan, Chemica Scripta 21, 43-53, 1983.

"The Nature and Distribution of the Metal Centers in Cytochrome c Oxidase," Sunney I. Chan, Gary W. Brudvig, Craig T. Martin, and Tom H. Stevens, in Electron Transport and Oxygen Utilization, Chien Ho, ed., Elsevier, Amsterdam, 171-177, 1982.

"The Nature of CuA in Cytochrome c Oxidase," Tom H. Stevens, Craig T. Martin, Hsin Wang, Gary W. Brudvig, Charles P. Scholes, and Sunney I. Chan, J. Biol. Chem. 257, 12106-12113, 1982.

"Reactions of Nitric Oxide with Tree and Fungal Laccase," Craig T. Martin, Randall H. Morse, Robert M. Kanne, Harry B. Gray, Bo G. Malmström, and Sunney I. Chan, Biochemistry 20, 5147-5155, 1981.

Other publications

Software Review of (curve fitting software) "pro Fit 5.01 for the Mac" J. Am. Chem. Soc. 119(30), 7171-7172, 1997.

Book Review: "DNA-Protein Interactions: Principles and Protocols, 2nd. Edition," Edited by Tom Moss, Craig T. Martin, ChemBioChem 4(6), 546, 2003.


Recent Seminars

June 2007 FASEB Summer Conference on Initiation of Transcription in Prokaryotes, Saxtons River, VT
February, 2007 Minority Biomedical Research Program, Cayey University College, Cayey, Puerto Rico
Nov xx, 2006 FASEB Summer Conference on Initiation of Transcription in Prokaryotes, Saxtons River, VT
Nov 6, 2006 The Pennsylvania State University, University Park
Nov 16, 2005 University of Connecticut
Apr 29, 2005 University of California at Santa Barbara
Nov 10, 2004 Brandeis University
May 1, 2003 Case Western Reserve University
April 30, 2003 Hofstra University
Nov 12, 2002 University at Albany
March 18, 2002 Dept of Biochemistry and Molecular Biology, Pennsylvania State Medical Center, Hershey, PA
March 16, 2002 MCB Annual Retreat, University of Massachusetts, Amherst, MA
February 23, 2002 Annual Meeting of the Biophysical Society, San Francisco, CA, Fluorescence Subgroup Meeting
July 2001 FASEB Summer Conference on Initiation of Transcription in Prokaryotes, Saxtons River, VT
November 10, 1999 Department of Chemistry, University of Massachusetts at Dartmouth
May 27, 1999 Centro de Biologia Molecular "Severo Ochoa," Universidad Autónoma de Madrid, Spain
May 17, 1999 Institut Pasteur, Departement de Biologie Moleculaire, Paris, France
April 15, 1999 Department of Biology, University of Indiana, Bloomington, IN
April 2, 1999 Department of Chemistry, Wesleyan University, Middletown, CT
April 23, 1998 Department of Chemistry, State University of New York at Buffalo
March, 1998 Minority Biomedical Research Program, Cayey University College, Cayey, Puerto Rico
February 3, 1998 Department of Immunology and Microbiology, State University of New York at Brooklyn
January 22, 1998 Department of Chemistry, University of Pennsylvania
October 5, 1997 Department of Chemistry, California Institute of Technology
April 28, 1997 Program in Molecular & Cellular Biology, University of Massachusetts
April 17, 1997 Department of Biochemistry, Louisiana State Medical Center

Craig T. Martin
EMail: CMartin@Chem.UMass.edu