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Representative
recent publications: scroll down or click here for a complete list of our publications 2008 I.A. Kaltashov, R.R. Abzalimov, S.J. Eyles, and A.
Frimpong. Studies of intact proteins and protein complexes: ESI MS approaches.
In: Mass Spectrometry Analysis for
Protein-Protein Interactions and Dynamics.
M. Chance, editor. Boston: Wiley-Blackwell, 2008, in press W.P. Griffith,
A. Mohimen, R.R. Abzalimov and I.A. Kaltashov. Characterization of Protein
Higher Order Structure and Dynamics with ESI MS. In: Comprehensive
Analytical Chemistry, Volume 52: Mass Spectrometry of Proteins. J.P. Whitelegge, ed. San Diego, CA: Elsevier, 2008, 47-62 2007 V. Sjoelund and I.A. Kaltashov. Transporter-to-trap
conversion: a disulfide bond formation in cellular retinoic acid binding
protein I mutant triggered by retinoic acid binding irreversibly locks the
ligand inside the protein. Biochemistry
2007, 46, 13382-13390
A.K.
Frimpong, R.R. Abzalimov, S.J. Eyles and I.A. Kaltashov. Gas-phase interference-free analysis of
protein ion charge-state distributions: detection of small-scale
conformational transitions accompanying pepsin inactivation. Anal.
Chem. 2007, 79, 4154-4161 W.P.
Griffith, I.A. Kaltashov. Protein
conformational heterogeneity as a binding catalyst: ESI MS study of
hemoglobin H formation. Biochemistry, 2007, 46,
2020-2026 2006 I.A.
Kaltashov. Macromolecular
conformations in solution from charge-state distributions produced by
electrospray ionization. In: Encyclopedia
of Mass Spectrometry, Vol. 8: Molecular Ionization. M. L. Gross, ed. San
Diego, CA: Elsevier, 2006, pp. 746-756 R.R.
Abzalimov and I.A. Kaltashov. Extraction
of local hydrogen exchange data from HDX CAD MS measurements by deconvolution
of isotopic distributions of fragment ions. J. Am. Soc. Mass
Spectrom., 2006, 17, 1543-1551 I.A. Kaltashov, M. Zhang, S.J. Eyles and R.R.
Abzalimov. Investigation
of structure, dynamics and function of metalloproteins with electrospray
ionization mass spectrometry. Anal. Bioanal. Chem., 2006, 386, 472-481 M. Zhang and
I.A. Kaltashov. Mapping of protein disulfide bonds using
negative ion fragmentation with a broadband precursor selection. Anal.
Chem., 2006, 78, 4820-4829 R.R.
Abzalimov, A. Frimpong and I.A. Kaltashov. Gas
phase processes and measurements of macromolecular properties in solution: on
the possibility of false-positive and false-negative signals of protein
unfolding. Int. J. Mass Spectrom., 2006, 253,
207-216 2005 I.A. Kaltashov and S.J. Eyles. Mass
Spectrometry in Biophysics: Conformation and Dynamics of Biomolecules. New York: John Wiley & Sons, Inc., 2005 (ISBN
0-471-45602-0) J.K. Hoerner, H. Xiao and I.A.
Kaltashov. Structural
and dynamic characteristics of a partially folded state of ubiquitin revealed
by hydrogen exchange mass spectrometry. Biochemistry, 2005,
44, 11286 –11294 I.A. Kaltashov and A. Mohimen. Estimates
of protein surface areas in solution by electrospray ionization mass
spectrometry. Anal. Chem., 2005, 77,
5370-5379 H. Xiao and I.A. Kaltashov. Transient
structural disorder as a facilitator of protein-ligand binding: native H/D
exchange - mass spectrometry study of cellular retinoic acid binding protein
I. J. Am. Soc. Mass Spectrom., 2005, 16,
869–879 I.A. Kaltashov. Probing protein
dynamics and function under native and mildly denaturing conditions with
hydrogen exchange and mass spectrometry. Int. J. Mass Spectrom., 2005, 240, 249-259 H. Xiao, J.K. Hoerner, S.J. Eyles, A.
Dobo, E. Voigtman, A.I. Mel’čuk and I.A. Kaltashov. Mapping
protein energy landscapes with amide hydrogen exchange and mass spectrometry.
I. A generalized model for a two-state protein and comparison with experiment.
Protein Sci., 2005, 14, 543-557 2004 and before M. Zhang, D.R. Gumerov, A.B. Mason
and I.A. Kaltashov. Indirect
detection of protein-metal binding: Interaction of serum transferrin with In3+
and Bi3+. J. Am. Soc. Mass Spectrom., 2004,
15, 1658-1664 J.K. Hoerner, H. Xiao, A. Dobo and I.A. Kaltashov. Is
there hydrogen scrambling in the gas phase? Energetic and structural
determinants of proton mobility within protein ions. J. Am.
Chem. Soc., 2004, 126, 7709-7717 W.P. Griffith and I.A. Kaltashov. Highly
asymmetric interactions between globin chains during hemoglobin assembly
revealed by electrospray ionization mass spectrometry. Biochemistry,
2003, 42, 10024-10033 A. Mohimen, A. Dobo, J.K. Hoerner and I.A. Kaltashov. A
chemometric approach to detection and characterization of multiple protein
conformers in solution using electrospray ionization mass spectrometry.
Anal. Chem., 2003, 75, 4139-4147 D.R. Gumerov, A.B. Mason and I.A. Kaltashov. Inter-lobe
communication in human serum transferrin: metal binding and conformational
dynamics investigated by electrospray ionization mass spectrometry.
Biochemistry, 2003, 42, 5421-5428 H. Xiao, S.J. Eyles and I.A. Kaltashov. Indirect
assessment of small hydrophobic ligand binding to a model protein using a
combination of ESI MS and HDX/ESI MS. J. Am. Soc. Mass
Spectrom., 2003, 14, 506-515 I.A. Kaltashov and S.J. Eyles. Studies
of biomolecular conformations and conformational dynamics with mass
spectrometry. Mass
Spectrom. Rev., 2002, 21, 37-71 A. Dobo and I.A. Kaltashov. Detection
of multiple protein conformational ensembles in solution via deconvolution of
charge state distributions in ESI MS. Anal. Chem., 2001,
73, 4763-4773 D. Gumerov and I.A. Kaltashov. Dynamics
of iron release from transferrin N-lobe studied by electrospray ionization
mass spectrometry. Anal. Chem., 2001, 73,
2565-2570 S.J. Eyles, P. Speir, G. Kruppa, L.M. Gierasch and I.A. Kaltashov. Protein
conformational stability probed by Fourier transform ion cyclotron resonance
mass spectrometry. J. Am. Chem. Soc., 2000, 122, 495-500 |
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