Professor
B.S. (Honors) 1985, Illinois Institute of Technology; M.Phil.,
1987; Ph.D., 1990, Yale University; NSF Postdoctoral Fellowship,
1990, M.I.T.
Organic Chemistry
Supramolecular chemistry of biological and materials systems.
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Principal Research Interests
 A key issue in the use of nanomaterials is controlling the interfacial interactions of
these complex systems. Our research program focuses on the tailoring of interfaces through the atomic-level control provided by organic synthesis. Using these tailored monolayers, we have developed particles for biological applications, including highly effective gene and drug delivery agents and sensors for the identification of pathogens. Concurrently, we are using nanoparticles as building blocks for the creation of new functional materials. In our research we couple synthetic capability with nanomaterials characterization and top-down fabrication techniques, providing access to materials an devices structured on all length scales. Underlying our efforts to create functional materials is an abiding curiosity of the fundamental nature of soft materials, including supramolecular assembly, collective and emergent behavior, surface science, and interfacial phenomena.
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| Representative Publications
“Rapid and Efficient Identification of Bacteria Using Gold Nanoparticle-Conjugated Polymer Constructs,” R.L. Phillips, O.R. Miranda, C.-C. You, V.M. Rotello and U.H.F. Bunz, Angewandte Chemie, in press (2008).
“Controlled Fluorination of FePt Nanoparticles: Hydrophobic to Superhydrophobic Surfaces,” Y. Ofir, B. Samanta, P. Arumugam and V.M. Rotello, Adv. Mat. 19, 4075-4079 (2007).
“Integrated Magnetic Bio-Nanocomposites through Nanoparticle-Mediated Assembly of Ferritin,” S. Srivastava, B. Samanta, B.J. Jordan, R. Hong, Q. Xiao, M. Tuominen and V.M. Rotello, J. Am. Chem. Soc.129, 11776-11780 (2007).
“Detection and Identification of Proteins using Nanoparticle-Fluorescent Polymer ‘Chemical Nose’ Sensors,” C.-C.You, O.R. Miranda, B. Gider, P.S. Ghosh, I.-B. Kim, B. Erdogan, S.A. Krovi, U.H.F. Bunz and V.M. Rotello, Nature Nanotech. 2, 318-323 (2007).
“Controlled Formation of Patterned Gold Films via Site-Selective Deposition of Nanoparticles onto Polymer Templated Surfaces,” H. Xu, R. Hong, X. Wang, R. Arvizo, C.-C. You, B. Samanta, D. Patra, M.T. Tuominen and V.M. Rotello, Adv. Mat. 19, 1383-1386 (2007).
Click Here for a complete list of publications.
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