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The investigation of molecular structure
and mechanistic processes is fundamental to chemistry at all levels.
Analysis, detection, spectroscopy, microscopy and many other tools
of physical and
analytical chemistry fall into this broad and vital area. Various
types of instrumental analysis are carried out by many groups, some
of which are primarily interested in development of methodology,
and some of which aim to apply modern physical and instrumental techniques
to investigate important chemical and biological problems.
Campus
and departmental facilities for instrumental chemistry are superb.
In addition to individual investigator equipment including circular
dichroism, fluorescence, laser spectroscopy, polarizing microscopy,
and stop-flow kinetic analysis, a variety of large facilities are
available to the
campus community (many for hands-on use). These include the Nuclear
Magnetic Resonance Facility, the Mass Spectrometry and Molecular
Weight Facility, the X-ray Structure Determination Facility, and
the W. M. Keck Microscopy Facility. See the Facilities link above
for more details.
A major strength of the department is experimental
bioanalytical and biophysical chemistry. A wide array of methodologies
are being applied to biological problems ranging from calorimetry
to microscopy, from magnetic resonance to absorption and emission
spectroscopy, from high performance liquid chromatography to surface
plasmon resonance mass spectrometry. This broad area of strength
is combined with other strengths in mathematical analysis of signal
output, linkage of separations technology to detection technology,
and application of new magnetic resonance methods to structure
determination (among others).
For participating faculty see Research
Matrix.
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